Ivermectin is a new-type broad-spectrum, highly effective, and low-toxicity antibiotic antiparasitic drug, which has a good killing effect on internal and external parasites, especially nematodes and arthropods. However, it is ineffective against tapeworms, flukes, and protozoa. The antiparasitic effect of macrolide antiparasitic drugs on nematodes and arthropods lies in increasing the release of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) in the parasite, opening the Cl⁻ ion channels controlled by glutamate, and enhancing the permeability of the nerve membrane to Cl⁻. This blocks the transmission of nerve signals, eventually causing nerve paralysis, loss of muscle cell contractility, and leading to the death of the parasite.

Broadening the deworming scope: The combined use has a strong killing effect on nematodes, trematodes, cestodes and arthropods, covering almost 99% of parasites.

Killing internal and external parasites: The combined use can kill both internal and external parasites. In particular, it is effective against external parasites such as mites, ticks and warble flies, eliminating the trouble of external deworming.

Killing adult worms and eggs: The combined use can not only kill adult worms inside and outside the body, but also directly or indirectly kill eggs, achieving a thorough deworming effect.