OTC Class B

Instructions for Cobamamide Tablets

Please read the instructions carefully and use as directed, or purchase and use under the guidance of a pharmacist.

[Drug Name]

Generic Name: Cobamamide Tablets    English Name: Cobamamide Tablets    Pinyin: Xiàngān Gu’ān Piàn

[Ingredients] Each tablet contains 0.25mg of cobamamide (C₇₂H₁₀₀CoN₁₈O₁₇P). Excipients: starch, sucrose, dextrin, magnesium stearate.

[Description] This product is sugar-coated tablets, pink after removing the coating.

[Pharmacological Category] This product is a vitamin class over-the-counter drug.

[Indications] Used for megaloblastic anemia and nutritional anemia caused by vitamin B₁₂ deficiency. It can also be used as adjuvant treatment for nutritional disorders and leukopenia caused by radiation and drugs.

[Specification] 0.25mg

[Usage and Dosage] Oral administration. Adults: 2-6 tablets (0.5-1.5mg) each time, 3 times a day.

[Adverse Reactions] Occasionally causes allergic reactions.

[Contraindications] Not yet known.

[Precautions]

1. Consult a physician before the first use and have regular medical examinations during treatment.

2. Pregnant women and lactating women should use under medical guidance.

3. Use with caution in patients with nervous system damage before a clear diagnosis is made.

4. Contraindicated in those allergic to this product; use with caution in allergic individuals.

5. Do not use if the product's characteristics change.

6. Keep out of reach of children.

7. Children must use under adult supervision.

8. Consult a physician or pharmacist before using with other medications.

9. Drug Interactions: May interact with other drugs; consult a physician or pharmacist for details.

[Pharmacological Actions] This product is a vitamin drug and a congener of cyanocobalamin (vitamin B₁₂). It is one of the two active coenzyme forms of vitamin B₁₂ in the body. Vitamin B₁₂ deficiency can cause anemia and neurological damage, leading to neurological symptoms such as depression, memory loss, and limb tremors.

[Storage] Store in a dark place and seal.

[Packaging] Oral solid medicinal HDPE bottle packaging. 100 tablets/bottle; 12 tablets/plate × 3 plates/box; 12 tablets/plate × 5 plates/box; 18 tablets/plate × 3 plates/box.

[Validity Period] 24 months

[Executive Standard] Chinese Pharmacopoeia (2020 Edition, Volume II)

[Approval Number] State Drug Approval No. H20083610

[Instruction Revision Date] March 13, 2023

[Marketing Authorization Holder]

Marketing Authorization Holder: Ningxia Zhouyang Pharmaceutical Co., Ltd.    Address: Wangyuan Development Zone, Yongning County, Yinchuan City, Ningxia

[Manufacturer]

Company Name: Ningxia Zhouyang Pharmaceutical Co., Ltd.    Production Address: Wangyuan Development Zone, Yongning County, Yinchuan City, Ningxia    Postal Code: 750101    Telephone: 0951-8462720    Fax: 0951-8462717    Website: www.zhouyangzhiyao.com.cn    For inquiries, contact the manufacturer.